月度归档： 2025 年 4 月

80% of the clinical data of new drugs are involved in fraud, which link has gone wrong？

　　According to official website data of the State Food and Drug Administration, as of January 21st, 2016, due to the untrue and incomplete clinical trial data, the number of drug registration applications rejected by the State Food and Drug Administration and withdrawn by pharmaceutical companies for self-examination was as high as 1,184, accounting for 73% of the total number required for self-examination. If 165 clinical exemptions are deducted, the proportion will reach 81%.

　　The staff of the food and drug department said that during the verification, it was found that the clinical trial data of many drugs were incomplete, the analysis data had no differential trajectory, and some data could not be traced back. Other companies deliberately concealed or omitted the adverse reaction records, and revised the test data that failed to meet expectations.

　　At the beginning of September, a report that "80% of the clinical data of new drugs are involved in fraud, and the regulatory links are falling behind" caused a shock. The direct consequence of clinical data fraud is poor efficacy. To some extent, clinical data fraud affects everyone.

　　According to the news, over 80% of the clinical data of new drugs have been found to be fake since china food and drug administration started the self-inspection and verification of drug clinical trial data one year ago, and the regulatory links behind them have fallen behind, and the violations of relevant subjects such as pharmaceutical companies, intermediaries and doctors are prominent.

　　The data of drug clinical trials are of great significance in drug research and development innovation, and standardized clinical trials with reliable data are the key link to ensure drug quality. As the last link of new drug research and development, whether the drugs developed with tens of millions or even hundreds of millions of yuan have curative effect and safety depends mainly on the experimental data. The falsification of drug clinical trial data will not only bring huge security risks to patients’ medication, but also affect the innovation and upgrading of China’s pharmaceutical industry.

　　status

　　Fraud in clinical trials is no longer news.

　　The results of clinical trials are not only the only standard to test the safety and effectiveness of drugs, but also the key basis for drug registration and listing. Pei yu, director of the Department of Pharmacy, School of Pharmacy, Jinan University, said that clinical trials with strict specifications and reliable data are a key safety barrier before the drug goes on the market, and also the core basis for drug supervision departments to support the drug listing. However, the survey found that it is no longer news that Chinese drugs were faked in the clinical trial stage before listing.

　　Data fraud began in preclinical research. "Before a drug goes on the market, human clinical trials must be done. However, from the moment the subjects were selected to join the group, fraud occurred all the time. " The person in charge of a pharmaceutical company, who asked not to be named, said that clinical trials often adopt the method of "competitive enrollment". The number of participants in the group will directly determine the doctor’s signature ranking and the amount of scientific research funds in the future. If a project needs 100 patients who meet the test requirements, but it does not get enough people before the planned date, the test may start with only 80 or even 60 people. In the face of lack, data can only be fabricated from scratch.

　　Not only that, the actual operation record is not true and it is also a common means of fraud. According to a survey conducted by China Journal of Clinical Pharmacology in 2013 on domestic experimental institutions, the proportion of non-standard experimental records is as high as 85.7%, which is the most problematic link in clinical trials, and only 1/7 institutions in China have not found any problems.

　　Fraud may appear in any link of clinical trials.

　　It is a consensus in the medical field that generic drugs should be equal to the original drugs in dosage form, specification, quality, efficacy and indications. Some pharmaceutical companies launch generic drugs in order to maximize profits, but the necessary link of clinical trials is often "ignored". The boss of a large biopharmaceutical company revealed that 90% of domestic generic drugs could not meet the original research standards. In order to pass the evaluation, it is very common to conceal data and selectively use data, and pharmaceutical companies even modify data in conjunction with doctors.

　　"The clinical data of drugs are untrue and irregular, and the reasons may not all be caused by enterprises." The general manager of a pharmaceutical company in Zhejiang said that there are many reasons and motivations, which may appear in any link of the whole chain of clinical trials. On the one hand, China’s current laws and regulations on drug clinical trial supervision are still not perfect; On the other hand, the number of drug clinical trial institutions is too small, which is seriously mismatched with the number of projects that need to carry out clinical trials every year, which leads to the overwhelming burden of clinical trial institutions and affects the quality and standardization of clinical trials.

　　question

　　Data fraud supervision is still "soft"

　　The extremely important data in clinical trials of new drugs are often ignored nowadays. In foreign countries, data statistics need to spend hundreds of thousands or even millions of RMB, while data statistics in China hospitals only need to spend tens of thousands of RMB.

　　China implements the qualification certification system for clinical trial institutions, that is, only clinical institutions that have passed the examination and approval of drug supervision departments can participate in clinical trials. The actual situation is often that it is very difficult for new drug trials to enter phase I clinical trials, but once they enter, they will be smooth all the way.

　　Traditionally, pharmaceutical companies often send inspectors (CRA) to supervise clinical trial institutions. After the clinical trial, CRA will collect the approved data and hand it over to the data processing institution for analysis and collation, and finally form the data and report submitted to the Drug Evaluation Center of the Food and Drug Administration for review. However, due to the lack of third-party supervision and checks and balances, hospitals as clinical trial institutions have frequent problems. In order to achieve the purpose of approval, some pharmaceutical companies will also modify the data in conjunction with statistical units. Although the General Administration clearly stipulates that if the clinical research data is fraudulent, the applicant’s new application for drug registration will not be accepted within 3 years, and the clinical trial data of the person directly responsible for participating in the research or organizing the research will not be accepted within 10 years. However, for a series of data fraud problems, supervision is still "soft".

　　Dr Liao Guojuan, CEO of Suzhou Jinweizhi Biotechnology Co., Ltd. said that in the United States, once data fraud occurs, pharmaceutical companies and R&D personnel will be blacklisted and will not be allowed to enter related fields for life.

　　counter-measure

　　New drug research and development must take the right path

　　Since April 2015, a number of new policies for drug trial reform have been introduced almost every month. On November 11th, last year, china food and drug administration also published the Announcement of china food and drug administration on Several Policies of Drug Registration Review and Approval in its official website, and put forward ten heavy new regulations, such as improving the approval standard of generic drugs and optimizing the review and approval of clinical trial applications. This may be a blessing for the creation of real new drugs with clinical value. However, after a lapse of one year, the news that 80% of the clinical data of new drugs are suspected of being falsified still broke out, which has to make people ponder: which link has gone wrong?

　　For the current situation of new drug research and development, the general manager of a pharmaceutical company in Nanjing feels very helpless: formal enterprises take the right path, only to find that enterprises that resort to deceit and cut corners are faster than their own approval.

　　The president of a biotechnology company in Shenzhen also said that many innovative companies that focus on drug research and development have made an innovative drug for ten years, and the data have been carefully made, but they have suffered losses when competing with companies that falsify data. "Strict review of clinical research data should not only be implemented early, but also be promoted. Although the progress of regular products may be affected in the short term, after the normalization, on the whole, it is conducive to the healthy development of innovative enterprises. "

　　Encourage real innovation with the strictest system

　　Some people in the medical field believe that there are two negative arguments to be vigilant at present: first, the introduction of policies should conform to China’s national conditions, and the requirements for innovation at this stage should not be too advanced; Second, the policy cannot be uniform, and some clinical data are just not standardized, not fraudulent, and should be allowed to exist.

　　In this regard, experts suggest that to ensure the authenticity of drug clinical data, we can refer to the advanced and mature practices in Europe and America, and have zero tolerance for clinical data fraud and other chaos, so as to effectively ensure the safety of patients’ medication; At the same time, more doctors should be allowed to engage in drug clinical trials and control the quality of clinical trials; Establish a third-party supervision system and strengthen supervision. In addition, electronic information technology can also be used to establish a database of drug clinical trials, requiring clinical institutions to report clinical trial data in real time and make it public, so as to realize universal supervision.

　　Authorities in the industry said that at present, it is a critical period to control "bad money drives out good money" in the field of drugs, and real innovation must be encouraged with the strictest system. Therefore, it is called for the revision of the "Quality Management Standards for Drug Clinical Trials" and other laws and regulations as soon as possible to further improve the system supervision; At the same time, the internal supervision system of pharmaceutical companies should be established to truly form core competitiveness through innovation. (Reporter Li Ying)

Super Mario Bros. Movie has exceeded $1.2 billion at the global box office.

1905 movie network news It is reported that the box office performance of the film continues to climb, and the global box office of the film has exceeded $1.2 billion, reaching $1.21 billion! Super Mario Bros. Movie not only became the first "Billion Club" movie in 2023, but also the highest-grossing movie in the world this year. At the same time, the film is also the total box office champion of the film history of game adaptation.


It is reported that "Hollywood Report" once conducted a survey on the adaptation of movies from games. The survey concluded that Nintendo’s Super Mario Bros. is the game adaptation film that Americans most want to see, so the film is generally optimistic at the North American box office. In the sixth week of its release in North America, Super Mario Bros. Movie reached US$ 13 million, a decrease of only 30.1% compared with the previous weekend. The cumulative total box office in North America was US$ 530 million, rising to the 24th place in the single box office of North American film history and the 5th place in the box office of animated films of film history. At the same time, the film also created the highest box office record for lighting and entertainment.


The film grossed $26.1 million overseas over the weekend, totaling $674.5 million (including 164 million yuan at the box office on the 41st day of its release in mainland China)! Overseas ticket warehouses include Mexico, Britain, Japan, France, Germany, Australia, Spain, Brazil, China and Italy. Among them, Japan, the hometown of Mario Brothers, ranked third in overseas ticket warehouses with a box office of 59.8 million US dollars, Mexico ranked first with a box office score of 82.4 million US dollars, followed by the United Kingdom with 63.2 million US dollars.


Super Mario Bros. is the best-selling game series in history. After its first release in 1981, it became popular all over the world. The film and television circle has put it on the screen several times. This film was jointly created by Nintendo and Lighting Entertainment, with the voices of Seth Rogan, Jack Black and Jigan michael kay.


At present, no sequel has been exposed.


Spring Festival collection! The outpatient scheduling schedule of some 3A hospitals in Sichuan is coming (I)

Hou Wenjin Sichuan Online Reporter Wei Feng

What should I do during the Spring Festival in the Year of the Loong? Chuanguan News and Popular Health News comprehensively sort out the Spring Festival scheduling time of some top three hospitals in Sichuan, and look at it together ↓

1. west china hospital

The emergency department operates normally 24 hours a day, and the online clinic operates normally. Offline clinics (the main campus and Wenjiang campus) will have a holiday for three days: from February 10th to February 12th, including blood sampling and auxiliary examination departments. The clinic resumed on February 13th.

2. Sichuan Provincial People’s Hospital

During the Spring Festival holiday in 2024, the outpatient service arrangements of Sichuan Provincial People’s Hospital are as follows:

(1) Outpatients of the Hospital Headquarters, Institute of Dermatology and Venereology, East Hospital (Longquan Hospital) and Psychiatric Center (Wenjiang Hospital) on February 10th — Closed on February 12th (from New Year’s Day to New Year’s Day); February 13th — The clinic was opened on February 17th (from the fourth to the eighth day of the Lunar New Year). On February 4th, the shift is scheduled on Thursday, and on February 18th, the shift is scheduled on Friday.

(2) February 10th — It will be closed on February 17th (from the first day to the eighth day of New Year’s Day). February 18th is scheduled on Friday.

3. West China Second Hospital of Sichuan University

Normal consultation during the Spring Festival.

(1) Pediatrics, gynecology, obstetrics, reproductive endocrinology, reproductive medicine, medical genetics, andrology, traditional Chinese medicine, comprehensive internal medicine, comprehensive surgery, ophthalmology, otolaryngology, oral cavity, skin, anesthesia, special needs, plastic surgery clinic and other professions have experts and specialists visiting, among which there are experts in children’s health care, children’s neurological rehabilitation, children’s breathing, children’s otolaryngology and other professions who are particularly concerned. Friends of patients in need can make an appointment to register for treatment.

(2) The citizens in need should check and make an appointment for the expert number source through the WeChat WeChat official account of the Second Hospital of West China or the WeChat applet of the Maternal and Child Health Portal of West China.

(3) In addition, the Internet hospital is operating normally, which can be treated by online consultation or online expert team, and drugs can also be delivered home.

(4) Emergency services are provided 24 hours a day in the emergency department of the two hospitals.

4. West China Stomatological Hospital of Sichuan University

During the Spring Festival of 2024, the outpatient service of West China Stomatological Hospital of Sichuan University was closed for three days, from February 10th to February 12th, during which the emergency department opened normally. From February 13th, the outpatient clinic opened normally, and the hospital implemented non-emergency full appointment registration. Please make an appointment registration in advance through the official WeChat service number of West China Stomatological Hospital of Sichuan University.

5. West China Fourth Hospital of Sichuan University

The Spring Festival outpatient service is arranged as follows:

On February 9, 2024 (New Year’s Eve), the family visits were scheduled on Friday.

The clinic was closed on February 10th (New Year’s Day).

On February 11th (New Year’s Day), the clinic was closed (Sunday).

The clinic was closed on February 12th (the third day of New Year’s Eve).

On February 13th (the fourth day of Lunar New Year’s Day), visits were scheduled on Tuesday.

On February 14th (the fifth day of Lunar New Year’s Day), family visits were scheduled on Wednesday.

On February 15th (Lunar New Year’s Day), visits were scheduled on Thursday.

On February 16th (the seventh day of Lunar New Year’s Day), visits were scheduled on Friday.

On February 17th (the eighth day of Lunar New Year’s Day), visits were scheduled on Saturday.

February 18th (New Year’s Day) closed (Sunday)

6. The Fourth People’s Hospital of Sichuan Province (Huaxi Chunxi Hospital of Sichuan University)

[Note]:

1. All the places not specially marked are Chunxi Campus.

2. Morning clinic time: 08:00— twelve o’clock

3. Afternoon clinic time: 14:00— half past five p.m.

4. Full-day outpatient service: morning and afternoon outpatient service.

[Tel]:

Emergency 028-86718215

Chief Duty Officer 028-86677946

7. Sichuan Maternal and Child Health Hospital

During the Spring Festival holiday, you can still have a check-up, arrange a reasonable time for medical treatment and make an appointment in time.

Outpatient address and time:

1. Jinyang Campus: No.290, Shayan West Second Street, Wuhou District, Chengdu (8:00— 12:00，14:00— 17:30)。

2. Tianfu Campus: No.1515 Qihuang Second Road, Tianfu International Biological City, Shuangliu District, Chengdu (9:00— 12:00，13:00— 17:00)。

Emergency procedures:

Jinyang Hospital: emergency obstetric registration in emergency department, telephone number: 65978453;

Tianfu Hospital Area: Emergency Department Obstetrics Emergency Registration, Tel: 60671701.

8. Sichuan Cancer Hospital

According to the national Spring Festival holiday arrangements, the outpatient work arrangements in Wuhou Campus and Tianfu Campus are as follows:

February 9, 2024 (New Year’s Eve) — Holiday on February 17th (the eighth day of the first month);

Go to work on February 4 and February 18, arrange doctor visits on Monday on February 4 (Sunday) and arrange doctor visits on Friday on February 18 (Sunday).

During the holidays, patients who are referred to the primary level and who are in emergency oncology should go to Wuhou Hospital for emergency oncology treatment.

9. Sichuan Children’s Hospital

During the Spring Festival holiday in 2024 (from February 10 to February 17), the pediatric clinic opened normally. Please click "Huaxi Maternal and Child Health Portal" for specific outpatient arrangements and related shifts.

10. Affiliated Hospital of North Sichuan Medical College

The outpatient service is operating normally during the Spring Festival holiday, and the number source of the outpatient service is scheduled normally.

11. West China Tianfu Hospital of Sichuan University

Holiday time: On February 10th (Saturday, Grade One), February 11th (Sunday, Grade Two) and February 12th (Monday, Grade Three), the outpatient clinic will be closed for 3 days, and the emergency department will operate as usual. On February 13th (Tuesday, the fourth day of junior high school), the clinic will be opened normally, and no shift will be made at the weekend clinic (the clinic is not open yet). During the outpatient clinic, the outpatient blood collection and related auxiliary examination departments were suspended.

12. Chengdu Women and Children Central Hospital

(1) Central Campus (No.1617, Section I of Riyue Avenue, Qingyang District)

24-hour consultation in emergency and fever clinics

February 10-17: Gynecology, Pediatrics, Reproduction, Ophthalmology, Otolaryngology, Stomatology, Dermatology, Mammography, Catheter Maintenance Clinic.

From February 13 to 18, the children’s health department and the Chinese medicine department opened the clinic.

(2) Industrial Street Campus (No.32 Industrial Street, Qingyang District)

Obstetrics and gynecology, pediatric emergency 24-hour consultation

From February 10 to 17, the department of obstetrics and pediatrics opened a clinic.

From February 13th to 17th, the gynecological clinic was opened.

On February 16th and 17th, the Women’s Health Guidance Center opened its clinic.

(3) Taisheng Road Campus (No.137 Taisheng South Road, Qingyang District)

Pediatric emergency 24-hour consultation

Fever clinic (8: 00-12: 00 am; 13:00-17:00 pm).

From February 10 to 17, the outpatient clinic of pediatric internal medicine and pediatric surgery was opened.

From February 13th to 18th, the outpatient clinics of dermatology, stomatology, otorhinolaryngology, head and neck surgery and ophthalmology were opened.

(4) Dongcheng Genxia Street Campus (No.24, Dongcheng Genxia Street, Qingyang District)

No emergency

The gynecological clinic was opened from February 13th to 17th.

Consultation and service telephone: 028-63806390

13. Chengdu 363 Hospital

During the Spring Festival (from February 10, 2024 to February 17, 2024), emergency services were available 24 hours a day, and some clinics and medical technicians went to work as usual. Please pay attention to the information of sitting, scheduling and medical technical examination in the dual-hospital area of 363 Hospital, and make an appointment for registration at service terminals such as WeChat WeChat official account or self-service machines in advance. Now, we will inform you of the arrangements for medical and technical departments and outpatient clinics in Xipu Campus (24-hour consultation telephone number: 028-63800363) and Wuhou Campus (24-hour consultation telephone number: 028-61810363) as follows:

Arrangement of outpatient consultation in Wuhou Hospital ↓

Arrangement of outpatient consultation in Xipu Hospital ↓

Inspection arrangement of medical technology department during holidays in Wuhou campus ↓

Inspection arrangement of medical technology department during holidays in Xipu campus ↓

14. Affiliated Hospital of Chengdu University

(1) outpatient department consultation arrangement

February 10th — February 12th: General internal medicine, general surgery, otorhinolaryngology, head and neck surgery, ophthalmology, stomatology, gynecology, obstetrics, pediatrics, rehabilitation medicine and oncology are open all day; Chinese medicine department (Dr. Ran Lingli) was out-patient all day on February 11th.

February 13th — February 17th: The clinics in various specialties were opened normally, and the clinics in anorectal and dermatology departments of traditional Chinese medicine were opened on the morning of February 13th-17th, and acupuncture and moxibustion in traditional Chinese medicine was held on February 15th — On the morning of 17th, the clinic was opened, and the Chinese medicine department (Dr. Ran Lingli and Dr. Zhang Chaode) had a full-day clinic on February 17th.

February 10th — February 17th: The convenience clinic is closed. Please go to various specialties if you need it.

February 10th — February 17th: The physical examination center suspended the physical examination.

(2) Partial inspection and inspection arrangements

Department of Ultrasound Medicine, Radiology Department, Laboratory Department and Electrocardiogram Room: February 10th — It opened normally on February 17th, and both enhanced CT and magnetic resonance examination need to make an appointment.

Cardiac function examination: February 10th — On the morning of February 17th.

Gastroenteroscopy: On the morning of February 12th, 14th and 15th, you need to make an appointment in advance.

(3) Tips

Before coming to the hospital for treatment, you can make an appointment in the WeChat "Service Number of Affiliated Hospital of Chengdu University" in advance, and choose the treatment department and treatment time according to your needs to reduce your waiting time, which is convenient, fast and safe. The 24-hour service center provides you with consulting services 24 hours a day at 028-60868888.

15. The 416 Hospital of Nuclear Industry of the Second Affiliated Hospital of Chengdu Medical University

In 2024, the outpatient clinic will be closed for 3.5 days (on the afternoon of February 9 — On the third day of February 12), the emergency department operates as usual 24 hours a day. On February 13th (the fourth day), all departments in the outpatient department made normal visits, so the majority of patients were requested to arrange the visit time reasonably.Some inspection arrangements are as follows:

Radiology Department: Holidays CT only does plain scanning, not enhancement. February 14th (fifth day) — On February 17th (Grade 8), MRI only performed routine plain scan.

Gastroenteroscopy: Ordinary gastroscopy can be done in the morning of the fourth, sixth and eighth day, and painless gastroscopy can be made after the holiday.

Physical examination center: February 9 (afternoon) — The clinic was completely closed on February 17th and opened normally on February 18th.

Mente Window: February 13th — On the morning of February 17th, it will only be open for half a day, and it will take February 18th for special medicine and special medicine.

16. Chengdu Hospital of Integrated Traditional Chinese and Western Medicine

From February 10, 2024 to February 17, 2024, the outpatient and emergency departments of the hospital were opened normally.

17. Chengdu Second People’s Hospital

During the Spring Festival holiday in 2024 (February 10th — February 17) The outpatient and emergency departments will provide comprehensive and high-quality diagnosis and treatment services to protect your health. The specific work arrangements are as follows:

18. Chengdu Third People’s Hospital

During the Spring Festival, outpatient and emergency services will be opened normally.

Spring Festival shift schedule ↓

During the Spring Festival, the duty time of medical technology department:

Duty time of special outpatient service: 8: 00 on February 11th & mdash; 12:00 and 8: 00 on February 14th & mdash; twelve o’clock

Gastroenteroscopy appointment time: February 13th and February 17th at 8:00— half past five p.m.

Duty time of gastroscope room: 8: 00 on February 13th & mdash; 12:00 and 8: 00 on February 17th & mdash; twelve o’clock

Inspection, ultrasound, radiation, electrocardiogram, cardiac color ultrasound, pharmacy and other related departments operate synchronously and normally to ensure the smooth progress of outpatient service.

Appointment methods include: official WeChat appointment in WeChat official account, telephone appointment in the comprehensive service center of the hospital (028-61312288), appointment on the 114 telephone platform, appointment and registration in the manual window, etc.

19. The First Affiliated Hospital of Chengdu Medical College

The "Spring Festival" clinic is arranged as follows:

Outpatient, laboratory, radiology, ultrasound, electrocardiogram and other medical and technical departments are not stopped. Emergency department, internal medicine, surgery, gynecology, obstetrics, pediatrics, stomatology, ophthalmology, otolaryngology and other departments all make house calls, from 8: 00 am to 11: 50 am and from 14: 00 pm to 15: 00 pm.

Special medical examination:

1. Arrangements for the opening of digestive endoscopy center during the Spring Festival:

No clinic will be opened from February 10th to 12th (the first to the third day of junior high school).

February 13th-14th (the fourth and fifth day) at 8: 00 am & mdash; At 12:00, ordinary and painless gastroscopy, carbon 13 and carbon 14 examination were carried out.

8: 00 am from February 15th to 17th (6th to 8th) & mdash; At 12:00, ordinary and painless gastrointestinal endoscopy, carbon 13 and carbon 14 examination were carried out.

2. The neurology department brain function examination room:

EEG and psychological evaluation: Grade one to Grade eight; Transcranial Doppler (TCD): Grade 2 to Grade 8; Foaming experiment: fourth to eighth day; Transcranial magnetic stimulation therapy: grade four to eight; Electromyography and related examinations: Grade 5, Grade 7 and Grade 8. The first day to the third day is half a day in the morning, and the fourth day to the eighth day is all day.

20. Chengdu Fourth People’s Hospital

Emergency arrangement

February 10 (Grade One) to February 17 (Grade Eight): The emergency department is open 24 hours a day. Location: Yingmenkou Campus of Chengdu Fourth People’s Hospital.

Outpatient service arrangement

1. Camp Gate Campus

February 10th (Grade One) to February 17th (Grade Eight): Psychiatric expert clinic;

February 10th (Grade One) to February 17th (Grade Eight): Follow-up clinic;

February 15 (sixth day) to February 16 (seventh day): early intervention clinic of psychiatry;

February 16 (seventh day) to February 17 (eighth day): psychiatric specialist clinic;

February 15th (sixth day) to February 17th (eighth day): special medical clinic.

February 10 (the first day) to February 17 (the eighth day): the outpatient clinic of addiction medicine is closed; February 10th (Grade One) to February 17th (Grade Eight): The outpatient service of general internal medicine was closed.

2. Jiujiang Campus

February 10th (Grade One) to February 17th (Grade Eight): Anxiety and Depression Clinic (II);

February 13th (Grade Four) to February 17th (Grade Eight): Psychosomatic Medicine Clinic (I);

February 13th (Grade 4) to February 17th (Grade 8): psychotherapy clinic;

February 15 (sixth day) to February 17 (eighth day): emotional outpatient service for children and adolescents;

February 15th (sixth day) to February 17th (eighth day): special medical clinic.

February 10 (the first day) to February 17 (the eighth day): Li Ling Jiang National Medical Clinic closed;

February 10 (the first day) to February 17 (the eighth day): Duan Mingjun’s famous doctor studio clinic stopped;

February 10th (Grade One) to February 17th (Grade Eight): The follow-up clinic will be closed.

consulting telephone

Yingmenkou Campus: 028-87522430(8:00 to 17:30), Address: No.8, Huxiyi Lane, jinniu district, Chengdu.

Jiujiang Campus: 028-85641749(8:30 to 12: 00; 13:00 to 17:00), Address: No.105 Caojin Road, Majiasi Community, Jiujiang Street, Shuangliu District, Chengdu.

Reading： Tik Tok Goddess Ranking Tik Tok Super Popular online celebrity Ranking Tik Tok Goddess Ranking Tik Tok Super Popular online celebrity Ranking

　

Who is the most popular celebrity in Tik Tok? Who are the people in Tik Tok’s popularity rankings in 2019? PConline Xiaobian has compiled some for everyone.

Quyiting baby

Basic information

Nickname: Yi Ting You Morgen

Location: Beijing

Gender: Female

Birthday: November 27, 1996

Introduction: Yes, it is Qu Yiting’s work email address. Welcome to 646445071@qq.com.

Registration time:

2014-10-05

Zhang Xinyao id: zxy 19941019

　

A real dancer must be able to sing and dance, and the most important thing is to be able to flirt!

Tik Tok’s well-deserved first red man, Zhang Xinyao, with his handsome dance, charming face and, most importantly, the ability to flirt, let’s take a look at what made him the first red man in Tik Tok!

The number of likes of a video is currently 1.5 million, and the number is still rising, which should be the highest number of likes in Tik Tok at present. This video has also been played by various gods in Tik Tok, so you can find it yourself if you are interested!

Especially the emotional dance, the choreography with rich personal style, and the perfect appearance, it is difficult without fire!

Wu Jiayu id: jj1118

　

3.96 million fans and 14.83 million likes.

Single highest point likes 370 thousand

Multi-scene transformation, although a bit difficult, is cool.

Users who often use Tik Tok APP will find that it has developed from the first barbaric growth to the professional direction. In fact, it is not difficult to imagine that the same style of dance and the same music will inevitably bring homogeneous content.

How to stand out among them is the key to competition. Wu Jiayu is a leader in using multi-scene transformation techniques. From the subway station to the street, from the bedroom to the living room, the alternate shooting of different scenes is suspended, which not only strengthens the rhythm of the video, but also brings more visual stimulation to users.

In fact, there are also ways to use black lens to make transitions in TV movies. This professional shooting technique has a certain threshold for ordinary people, but it is not high. In fact, if you are willing to invest some time and energy, you can master this technique.

In Tik Tok, Wu Jiayu used his hands, clothes, etc. as a shelter, and with the filter effect of the APP, he finished the scene switching.

1. Q: Will you like me?

A: 1. No.2. Yes.

If the other party answers: No.

You can go on to say: Never mind, if not, I can teach you.

2. "I have nothing to talk about with you."

"In addition to falling in love."

3. "The first time I saw you, I thought you looked like a person."

"Like my future girlfriend/boyfriend."

4. Say to her: Yuanyuan, Yuanyuan, do you know which star I like?

She certainly doesn’t know.

Then he said, Gao Yuanyuan, do you know why? Because my favorite girl also has a round word in her name.

Note: Change different stars according to their names.

Please find out the repetition of this passage.

"Do you like me?"

Repetition: Yes

One-week inventory ｜ Alibaba’s US stocks fell by 2.01% last week, and Hong Kong stocks rose by 0.23%

[trend of individual stocks]

24-28 March

Last week, the S&P 500 fell 1.53%, the Nasdaq Composite Index fell 2.59% and the Dow Jones Industrial Average fell 0.96%.

Alibaba’s US stocks fell 2.01% last week.Last week, the total turnover was $10.45 billion. As of last week’s close, the US stock price was $132.43. The cumulative monthly decline of US share capital is 0.06%, the cumulative increase this year is 56.19%, and the cumulative increase in the past 52 weeks is 83.02%.

Last week, the Hang Seng Index fell by 1.11% and the Hang Seng Technology Index fell by 2.36%.

Alibaba -W Hong Kong stocks rose 0.23% last week.Last week, the total turnover was 49.839 billion Hong Kong dollars. As of last week’s close, the stock price of Hong Kong stocks was 131.00 Hong Kong dollars, with a market value of 2.49 trillion Hong Kong dollars. Hong Kong stocks rose 2.75% this month, 58.98% this year and 86.48% in the last 52 weeks.

[Company comparison]

Securities code Securities abbreviation Latest price Last week’s ups and downs Up and down this month Up and down this year 52-week ups and downs EBAY eBay $67.16 2.1% 3.74% 8.41% 27.25% VIPS Vipshop $16.13 -0.98% 2.61% 19.75% -2.54% JD JD.com $41.58 -1.56% -0.76% 19.93% 51.81% AMZN Amazon $192.72 -1.78% -9.21% -12.16% 6.84% BABA Alibaba $132.43 -2.01% -0.06% 56.19% 83.02% PDD Pinduoduo $120.45 -4.89% 5.95% 24.19% 3.61% BZUN Bao Zun Dian Shang $2.80 -6.67% -11.95% 2.94% 21.74% 06808 Gaoxin retail 1.89 hong kong dollars 2.72% 6.18% -23.79% 21.15% 09618 JD.COM Group -SW HK$ 164.40 0.92% 2.37% 20.88% 52.36% 09988 Alibaba -W HK$ 131.00 0.23% 2.75% 58.98% 86.48% 00493 Gome retail 0.02 Hong Kong dollars -5.56% -10.53% -15% -5.56% 09991 Bao Zun Dian Shang -W HK$ 7.50 -7.18% -7.98% 1.49% 25.42%

[Related News]

Longhu Group and Ant Group reached a strategic cooperation to explore the new experience of "touch" service.

Longhu Group and Ant Group signed a strategic cooperation agreement, and the two parties will devote themselves to exploring the innovative application of Alipay’s "touch" technology in business scenarios. In the future, Longhu Group will gradually launch "touch" payment and digital services in Longhu Tianjie Shopping Center nationwide, and consumers can complete safe and convenient payment only by lightly touching the device without opening Alipay APP. (People’s Financial News)

Xingji Meizu will release Meizu Note 16 series and access the Alibaba Cloud model.

Liao Qinghong, chief operating officer of Xingji Meizu, announced that Meizu Note 16 series will be released in April and a national appointment will be opened. Meizu 22 series is scheduled to be released this summer. At the same time, the cooperation between Xingji Meizu and Alibaba Cloud has been upgraded, and it has become the first mobile phone manufacturer to deeply access the Qwen2.5-Omni model, so as to improve the AI emotion understanding and complex task processing ability. (Interface News)

Alibaba Cloud released the end-to-end multi-modal AI model Qwen2.5-Omni-7B.

Alibaba Cloud released Qwen2.5-Omni-7B, the first end-to-end full-modal large model of Tongyi family. The model is specially designed for full-modal perception, which can handle multimodal inputs such as text, images, audio and video, and generate text and natural language responses in real time, setting a new standard for deploying multimodal AI in terminal devices such as mobile phones and notebook computers. Although only 7B parameters are lightweight, Qwen2.5-Omni-7B still shows excellent performance and powerful multi-modal ability, and becomes an ideal base model for developing AI agents with high efficiency, high cost performance and valuable use, especially in the field of intelligent voice applications. For example, real-time voice navigation can help the visually impaired to identify the surrounding environment safely, analyze the ingredients in the video to provide cooking guidance step by step, and create an intelligent customer service dialogue experience that truly understands the needs of customers. The model is now open source on Hugging Face and GitHub, and can be obtained through Qwen Chat and Alibaba Cloud open source community ModelScope. At present, Alibaba Cloud has opened more than 200 generative AI models. (Alibaba Cloud)

Taobao: Severely crack down on illegal behaviors such as using AI fake pictures to deceive consumers.

Taotian Group issued a document saying that starting from today, Taobao launched the AI ? ? fake map governance on the whole platform, and severely cracked down on the violations of using AI fake maps to deceive consumers and infringe on original brand businesses. Taobao stipulates that the product pictures should be reflected by the actual pictures of the products as the core effect, and the modification behavior should be moderate to avoid distortion. It is strictly forbidden to use AI and other technical synthesis methods to present a significantly distorted product information renderings that are inconsistent with the actual situation.

Taobao: This year, the investment in user growth has doubled, and the first-time consumers have increased several times in March.

Chu Duan, vice president of Alibaba Group and president of Taobao Platform Division, said at the 2025 Tmall Super Brand Private Sharing Meeting held on March 26 that the average daily first-time consumers of Taobao Tmall platform increased several times compared with the same period of last year in the first three months of 2025. Under the high user growth rate, Taobao Tmall will strengthen its support for businesses with good creativity and good service. In order to bring more consumers, the investment of Taobao Tmall platform for user growth this year will double compared with last year. (People’s Financial News)

Star map Wei Tianxin and Gaode map reached in-depth cooperation

Recently, Zhongke Xingtu WeiTianxin Technology Co., Ltd. (referred to as "Xingtu WeiTianxin") officially reached an in-depth cooperation with Gaode Map. Xingtu WeiTianxin uses meteorological technology to empower smart travel in new scenes, and deeply integrates the self-developed eTAPES Super-Grider Tianxin high-precision intelligent weather grid system into the navigation scene of Gaode Map APP, providing users with a more accurate and practical navigation experience and opening a new era of high-precision weather forecast navigation. In the future, Xingtu Weixin will further expand the cooperation field with Gaode Map, and plans to carry out in-depth cooperation in AI model forecasting and social observation to further realize "local accurate" weather forecasting. (People’s Financial News)

Vice President of Xiaomi Group: The monthly sales of Xiaomi 15 Ultra in Tmall increased by 50% compared with the previous generation.

Wang Xiaoyan, vice president of Xiaomi Group and president of China District, revealed at the exclusive meeting of Tmall 2025 TopTalk Super Brand that this year, Tmall has increased its investment in new product resources, and the support programs such as homepage recommendation, search weighting and live broadcast subsidy have accelerated the growth cycle of new products. It is understood that under the double blessing of Tmall brand potential and national subsidy policy, in the first quarter of 2025, Xiaomi increased by 50% year-on-year in Tmall, hitting a record high. Xiaomi 15 Ultra’s first transaction in Tmall exceeded 100 million, winning the first new product transaction, and the monthly sales volume of Tmall’s first sales increased by 50% compared with the previous generation. (36Kr)

() Sign a strategic cooperation agreement with Alibaba.

On March 26th, China Mobile and Alibaba held a signing ceremony of strategic cooperation agreement in Beijing. Yang Jie, Chairman of China Mobile, and Wu Yongming, CEO of Alibaba attended the signing ceremony. Chen Huaida, Deputy General Manager of China Mobile, and Wen Jia, President of Alibaba Public Affairs signed the agreement on behalf of both parties. According to the agreement, the two sides will carry out in-depth cooperation in digital infrastructure, application ecology, science and technology innovation capability and international business, jointly build and operate advanced AI data centers, help both sides improve the scale and efficiency of cloud computing and AI services, deepen the technical exchange and ecological co-construction of China Mobile’s "Nine Days" and Alibaba’s "Tongyi Qianwen" AI models, and promote the deep integration of AI with various industries to create greater industrial value. The signing of this contract marks a new stage of comprehensive strategic cooperation between the two sides. The two sides will build a new ecology of AI industry based on new potential energy such as cloud, computing power and large model. (People’s Financial News)

Last year, Tmall sold more than 4,100 brands, and in 2025, it will fully invest in big growth.

On March 26th, Tmall announced the latest business strategy in 2025: fully support high-quality brands and original brands, fully liberalize the incentive policies, and expand brand growth. Tmall also disclosed that the current number of active buyers in Amoy reached 1 billion. In addition, in 2024, more than 4,100 brands broke through the platform, an increase of 18% year-on-year; There are 34,000 super items with a turnover of over 10 million. Last year, the annual active buyers of Taobao Live increased by 38% year-on-year. (Interface News)

Alibaba and BMW reach AI cooperation.

It is reported today that BMW and Alibaba will deepen AI cooperation, and ali tong Yida model will be applied to BMW’s new generation series in China market. The two sides have no response to this. (Sina Technology)

Strategic adjustment of Ant Group: reducing traditional investment and increasing AI layout.

According to Sina science and technology news, Ant Group recently reduced its holdings of Obi Zhongguanghe (), and accumulated a return on investment of over 775 million yuan, which attracted market attention. This reduction is based on the adjustment of strategic direction, and ants turn their funds to cutting-edge scientific and technological fields such as artificial intelligence to support a new generation of scientific and technological innovation. Ant’s investment strategy is still oriented to the company’s strategy, focusing on AI big model, AI computing power, embodied intelligence and other directions, and has invested in a number of related enterprises. Ant emphasizes that it has a long holding period, pays attention to ecological synergy, promotes technological innovation through investment, and creates more value for society.

Zhejiang Provincial Government signed strategic cooperation agreements with Alibaba Group and Ant Group.

On the afternoon of 25th, Zhejiang Provincial Government signed a strategic cooperation agreement with Alibaba Group and Ant Group. Governor Liu Jie witnessed the signing of the contract with Cai Chongxin, Chairman of the Board of Directors of Alibaba Group, and Jing Xiandong, Chairman of Ant Group. According to the agreement, the provincial government, Alibaba Group and Ant Group will closely focus on "taking high-quality development as the primary task, narrowing the’ three major gaps’ as the main direction, taking reform and innovation as the fundamental driving force, and meeting people’s needs for a better life as the fundamental purpose", further integrate resources and work closely together to promote the healthy development of the platform economy, cooperate in artificial intelligence and other fields, better serve the Chinese-style modern provincial practice, and jointly promote the implementation of major national strategies. On behalf of the provincial government, Vice Governor lu shan successively signed agreements with Wu Yongming, CEO of Alibaba Group, and Han Xinyi, CEO of Ant Group. (Tide News)

Alibaba Cloud opened the largest campus recruitment of AI talents in recent years.

The reporter learned that Alibaba Cloud recently recruited AI technology reserve talents in the top universities in the world, and recruited the largest AI talent campus in recent years. It is understood that this recruitment is aimed at top universities in the world, such as Tsinghua University, Peking University, Zhejiang University, Massachusetts Institute of Technology and Stanford University, and recruits technical talents in the fields of large language model, multimodal understanding and generation, model application and AI Infra. At the same time, the project sets up the A Star project and the Al Clouder project, which are aimed at top talents with high-level papers and the influence of open source projects, and provide better salary and professional support for such graduates. This move is another AI talent strategy launched by Alibaba after the previous T project. (science and technology innovation board Daily)

Alibaba Cai Chongxin: I began to see a bubble in the construction of artificial intelligence data centers.

Cai Chongxin, chairman of Alibaba, said that he began to see the emergence of a bubble in the construction of artificial intelligence data centers, and many data center investment announcements in the United States were "repeated" or overlapped. He also said that the number of employees in Alibaba has bottomed out and will be "restarted and re-recruited", and the company will provide reasonable returns to shareholders through dividends. (Sina Finance)

Ant Group has introduced a new MoE language model, which uses domestic AI chips to train, and its performance is equivalent to that of completely using NVIDIA chips, dense models of the same scale and MoE models.

Recently, the Ling team of Ant Group published a technical achievement paper. The paper shows that Ant Group has launched two MoE large language models with different scales-Ling-Lite and Ling-Plus. The former has a parameter scale of 16.8 billion (activation parameter of 2.75 billion) and the Plus base model has a parameter scale of 290 billion (activation parameter of 28.8 billion), both of which have reached the leading level in the industry. In addition to the self-developed large model with leading performance, the biggest breakthrough of this technical paper is to propose a series of innovative methods to improve the efficiency and accessibility of AI development in a resource-limited environment. Experiments show that its 300-billion-parameter MoE (Hybrid Expert) model can complete efficient training on low-performance equipment using domestic GPU, and its performance is equivalent to that of NVIDIA chip, dense model of the same scale and MoE model. (science and technology innovation board Daily)

Ant Group launched two MoE language models with different scales, and the training cost was further reduced by using domestic AI chips.

Recently, the Ling team of Ant Group published a technical achievement paper. The paper shows that Ant Group has launched two MoE large language models with different scales-Ling-Lite and Ling-Plus. The former has a parameter scale of 16.8 billion (activation parameter of 2.75 billion) and the Plus base model has a parameter scale of 290 billion (activation parameter of 28.8 billion), both of which have reached the leading level in the industry. In addition to the self-developed large model with leading performance, the biggest breakthrough of this technical paper is to propose a series of innovative methods to improve the efficiency and accessibility of AI development in a resource-limited environment. Experiments show that its 300-billion-parameter MoE (Hybrid Expert) model can complete efficient training on low-performance equipment using domestic GPU, and its performance is equivalent to that of NVIDIA chip, dense model of the same scale and MoE model. (Securities Times)

[US stock rating]

On March 28th, Mizuho rated Alibaba as outperforming the market with a target price of $170.00.

This article comes from the theme of Hong Kong-US Datalink. Click to read more about Hong Kong-US companies > > >

Maoming, Guangdong issued the first flood red warning this year.

　　CCTV News:According to "Maoming released" WeChat WeChat official account news, affected by Typhoon Sanba and weak cold air, from October 19th to 20th, there was a large-scale rainstorm to a heavy rainstorm in Maoming. Maoming Hydrological Branch decided to upgrade the level IV emergency response of flood control hydrological forecasting to level III emergency response of flood control hydrological forecasting from 2: 00 on October 20th, further strengthen the duty on duty, and continuously do a good job in water and rain monitoring, forecasting and early warning.

　　Affected by continuous rainfall, the water level of rivers in Maoming area generally rose. According to the current water and rain situation and the future rainfall trend, Maoming Hydrological Branch has successively issued flood warnings for many rivers. Among them, Maoming Station of Xiaodongjiang is expected to reach the flood level of 12.5 meters, with the warning level exceeding 3.5 meters. Changshanyuan Station, Chejiaoshan Station and Baishacun Station along the river all exceed the warning level by more than 1 meter. The water level of Shatian Station of Shatian River in Gaozhou City has risen sharply, and it is expected that the warning level will exceed 3 meters, which may lead to dike overflow and dike break. Maoming Hydrological Branch issued the first red flood warning this year at 3: 00 on October 20th. In addition, Shatian River and Rudong River issued red flood warnings, Meihuajiang and Jianjiang issued orange flood warnings, Luojiang and Pingdingshui issued yellow flood warnings, and Caojiang, Xindong River, Huanghua River and Qianpai River issued blue flood warnings.

　　Maoming Hydrological Branch will closely monitor the water and rain conditions, provide accurate hydrological information forecast to relevant departments in time, provide scientific basis for flood control and disaster relief decision-making, and send information to remind relevant units along the river and the public to pay attention to dike safety and do a good job in defense, risk avoidance and disaster reduction.

Jiangling Fushun picked up the car for one month and the brakes failed, and the engine oil leaked for half a year. How did the quality checkpoint pass？

In today’s increasingly prosperous automobile market, consumers have high expectations for the quality and safety of automobiles. Recently, however, the quality problem of Jiangling Fushun has been greatly questioned by the owner.

In the complaint case of the automobile complaint network, we can see the worrying quality hidden trouble of Jiangling Fushun. Mr. Lu, the owner of the car, bought Jiangling Fushun on April 27, 2024, but within a short month of picking up the car, the brakes actually failed twice. As a key component of automobile safety, the importance of brake system is self-evident. Brake failure may lead to serious traffic accidents, endangering the safety of passengers in the car and other pedestrians and vehicles on the road. This is an unacceptable quality defect for a new car that has just been bought for a long time.

IMG_256

Not only that, but in less than half a year after picking up the car, the vehicle also leaked oil. As the heart of an automobile, the normal use and sealing of engine oil are very important. Oil leakage will not only affect the performance and life of the engine, but also cause fire and other safety hazards. These problems faced by Mr. Lu, the owner of the vehicle, are by no means accidental faults, but involve serious quality problems of the core components of the vehicle.

IMG_256

For such quality problems, the owner’s appeal is to ask the 4S shop or manufacturer to make a way to return the car. As a commodity, car owners have invested a lot of money and trust in the purchase. When the vehicle has such serious quality problems, the owner has the right to ask the manufacturers and dealers to give reasonable solutions. However, as of the date of publication, the problem of car owners’ demands has not been properly solved.

As a well-known automobile brand, Jiangling should have a higher standard and guarantee for its product quality. These problems in Jiangling Fushun make people question the production technology and quality control system of Jiangling. In the process of automobile production, the design, manufacture and testing of brake system and engine should be strictly checked. Why do these serious problems appear on a new car? Is the quality of the parts not up to standard, or is there a mistake in the production and assembly process? Or is there a loophole in the inspection link before the vehicle leaves the factory?

Nowadays, there are many automobile brands, and car owners often consider many factors such as brand reputation, vehicle performance, quality and after-sales service when choosing. Jiangling Fushun’s brake failure and oil leakage will undoubtedly have a negative impact on its brand image. Car owners may have doubts about other models of Jiangling brand because they are worried about quality problems, and then turn to other competitive brands. This is a problem that needs to be paid attention to and solved for Jiangling.

Click to view the image source.

For the owner, Mr. Lu, buying a car with quality problems not only brings economic losses, but also may cause a lot of inconvenience to life and work. In the factory where Mr. Lu is located, drivers are afraid to continue driving because of vehicle quality problems, which will inevitably affect the normal operation of the factory. For other potential car owners, such a case has also played a warning role, and it is necessary to choose brands and models more carefully when buying a car.

Car complaint network:

The quality problem of Jiangling Fushun should be highly valued by manufacturers. Manufacturers need to actively communicate with car owners, thoroughly investigate the causes of the problems and take effective measures to solve the problems. Only in this way can we regain the trust of car owners and maintain the reputation of the brand.

In the 1990s, children in Northeast China were eating ice cream all year round.

Original Li chi shou chi huo institute

Some time ago, the price of local ice cream in Northeast China rushed to the topic because it was too cheap. In fact, the price of local ice cream has not increased much in recent years. Except for some very famous online celebrity products, the price of most ice cream can meet the ideal of buying a big bag for 10 yuan.

As a child in Northeast China, I really miss the days when I wholesale popsicles in boxes and chew popsicles all year round!

The snowman is full of candied haws and popsicles.

01

Ice cream and popsicles

/Accompany the Northeast people all the year round/

More than 20 years ago in winter, a child in Northeast China bought a few cents roasted sweet potatoes at the school gate after school, covered his hands while eating, and his breath formed a white fog in front of his face. Then, less than an hour after I turned home, I dug out a popsicle from the ice cream box in the yard and began to chew …

In the past, my southern roommate asked me curiously, why are Northeasters afraid of cold and heat? I said, "Imagine that it is MINUS 30℃ outside the house and 20℃ above zero in the house in winter. When the temperature difference between indoor and outdoor reaches 50, are you afraid?"

Frozen food is usually required to be stored below MINUS 18℃. The outdoor temperature in winter in the three northeastern provinces is much lower than this. Eating ice cream in winter can also save electricity at home, and the balcony or yard of every household is a natural refrigerator. Ice cream, frozen meat and frozen fruit are neatly arranged, and it is not unusual to sell ice cream on the street.

Popsicles and ice cream are all on the table, freezer? No need! Tuchong creativity

It is precisely because of the particularity of the weather that ice cream is bought all year round, and ice cream brands are not worried about selling.

Around the 1990s, the "new three items" of China families replaced the "old three items", and refrigerators became more and more popular as common household appliances. There are fewer and fewer aunts walking around with ice cream boxes on their backs, and there are all kinds of ice cream packed independently in small shops.

Creative ideas of sorbet boxes in 1980s and 1990s.

In summer, the old railway in Northeast China is even more presumptuous. With a refrigerator at home, ice cream is bought by the box, and several neighbors can enjoy the discount price and wholesale directly from the ice cream factory. There is no middleman to earn the difference. If you want to buy it in bulk, you can also buy it at any time at the designated window in the ice cream factory.

When I was a child, I especially liked to go to the ice cream factory, which is different from the small shop. There is a thick wall outside the ice cream factory, and there are several small windows on the wall. The windows are well sealed. Every time a salesperson opens the small windows, he will take out air conditioning from the inside. In the era when there is no air conditioning, the ice cream factory is a luxury for me in summer.

Ice-cold ice cream factory (the picture and text don’t match) What a creative idea

02

Childhood Memories of Children in Northeast China

/Popsicle, ice cream, ice cream, everything/

There are popsicles, milk bricks and milk cakes in Northeast China, among which popsicles are the most. If you ask others to help you buy a popsicle, you can buy 7 or 8 brands. The early popsicles were almost the same, and they were basically original milk flavor. At that time, the inner roll of popsicles was not as powerful as it is now.

The freezer in the canteen shoots Li eating hands.

Milk bricks and milk cakes have higher milk content and can be eaten quickly in summer. Now the glutinous rice paste in Zhongjie, which sells for 50 cents, still tastes the same as before. When I first ate glutinous rice paste, it felt like a sticky bean bag frozen outside in winter at home. However, the glutinous rice skin is not sticky at all, and it is soft, thin and a little strong. The ice cream milk inside is sweet and not greasy, and it melts in the mouth. Later, I ate other glutinous rice cakes, the price was several times higher, and it was not very delicious.

Glutinous rice cake zjbd

There is also the ice cream with waffles and milk cakes, which children especially like. There is no ice cream stick, so you have to drag it with a packaging bag when you eat it, and you will accidentally melt it. For example, the milk tofu of Hongqi is wrapped in wafer cakes on all sides, with milk cakes in the middle; There are many sandwiches in the square cake on Sunday, some of which can resist hunger like eight-treasure porridge; There are also hundreds of Wafer Ice Cream from Sofia, which is also a very popular classic …

Red flag milk tofu, shoot Li Chishou.

To say that it is convenient to eat, the most powerful thing is this kind of sorbet. A hundred schools of thought won Sophia’s big bowl of sorbet. The sorbet is cut into small pieces, which can be used with a spoon, fork or chopsticks. It is convenient to eat without getting dirty hands. There are also ice cakes packed in bags by Lao Dingfeng, all of which give people a pleasure of swallowing ice cream.

Bagged sorbet laodingfeng

A bag of ice cubes with several flavors, such as Sprite and Coke, costs a few cents. When you buy it, open a bag and pour it into a big tea pot to soak in water. At that time, it was not popular to freeze your own ice, so it was convenient and convenient to eat it.

Frozen drinks shoot Li eating hands.

In summer, at the cold drink stand at the entrance of the railway station, you can also eat soft drinks to soak sorbet, dig out several spoonfuls of sorbet balls from the ice cream vat, put them in a plastic cup of about 500 ml, and then open a bottle of iced soft drinks and pour them in. Ice cakes in cold drink stalls generally have low milk content and few flavors to choose from, but they are enough to relieve summer heat.

In addition to these, there are many ice cream with age memory.

Shenyang Huanggu ice cream left in my memory has its own selling sound BGM. After Huanggu ice cream returned, it also submitted a "sound trademark" for applying for registration of selling sound.

Jin Zhiwen has a song called "Pingquan Road", and there are two lyrics singing "Ice cream, ice cream in Changchun Hotel". Ice cream, little cream ice cream. " What I’m talking about is the small cream ice cream in Changchun Hotel.

Compared with the grounding gas of local ice cream brands, foreign brands spend more time on the style of ice cream. And Lu Xue’s green tongue, let me know that ice cream can not only be eaten, but also "scare people", and I have to swing it around for a long time every time I eat it halfway.

Green tongue, shoot, shoot, shoot

At that time, Mengniu and Yili also enriched the ice cream patterns in the supermarket under various competitions, such as small pudding, milk raisins and green mood. What surprised me most at that time was that they updated their products quickly.

Xiao bu ding Shu tu chong creativity

03

Today’s Northeast Ice Cream Market

/Don’t mention it. Come and eat./

The Madiel Cold Drink Hall on Harbin Central Street is the punch-in point for tourists. Founded in 1906, Mattel is one of the earliest cold drink enterprises in China. There are many Russian-style buildings in Harbin. Mattel’s name is very exotic, but ice cream is a very simple strip. Different from other local brands that take the people-friendly route, the average price of Mattel today is more than 10 yuan, even in the high-end ice cream market.

The creative idea of Madiel cold drink hall in Central Street

In recent years, some brands of ice cream in Northeast China are very popular, such as Ruby (Northeast Big Board) and Baijiade, which are very popular with friends in the south. In 2019, when they were hungry, they released a map of China ice cream, and these ice creams were better in the province than in the local area.

Northeast Daban Tuchong Creativity

There are also some ice cream brands in online celebrity that have become popular recently because of their good product marketing, such as Aoxue (double egg yolk ice cream, Northeast pot-stewed), Zhongjie (1946 series), Madiel, De’s (Grando series), Humboldt (grass-burning ice cream), etc. Those who have no perseverance have all gone to chop their hands.

Online celebrity Xuegao Tuchong Creativity

In fact, it is easy to find ice cream decades ago in the freezer of the local supermarket. The owner of the small shop said that many old ice creams were upgraded and changed in packaging, but the inside remained unchanged.

.

The old-fashioned milk cake in the new package was shot by Li Chishou.

People in Northeast China love ice cream, which is not inferior to other cuisines. Many cities have unique ice cream memories. Northeast ice cream, like northeast old iron, is warm and practical, which can make you full and eat well.

What’s the smell of iron railings in the northeast?

Original title: "Northeast children in the 1990s are eating ice cream all year round."

Read the original text

How to excavate the era connotation of Yangming culture？ Experts describe Guiyang in their hearts

　　CCTV News:In 2008, Guiyang first put forward the Guiyang spirit of "unity of knowing and doing, striving for the first place through cooperation", and integrated Yangming culture into the urban spirit. The Guizhou Provincial Party Committee and the provincial government took Yangming culture as a key cultural business card during the 13th Five-Year Plan period, and regarded "the unity of heaven and man, knowledge and action" as the humanistic spirit of Guizhou, and the inheritance and development of Yangming culture gradually became a prairie fire.

　　How to understand the shaping of urban spirit by Yangming culture and explore the era connotation of Yangming culture? How to build a spiritual highland, boost the development of one side and benefit the people of one side? Let’s see how the experts describe it in the column "On Tao".

　　Describe Guiyang in your heart

　　Gu Jiu, former director of Guizhou Literature and History Research Institute:I want to talk about my feelings about Guiyang in the past, Guiyang today and Guiyang in the future from the perspective of a common people.

　　When we were young, there were basically no buildings in Guiyang. When we climbed to the East Mountain, we saw all the black tile houses, all of which were one floor, including the roof of our house, and the ceiling could be touched when we jumped up. As soon as the door is opened and closed, it is wooden, so there is a "ga". There is also a window. If you don’t hold it well, you will be scolded if the window paper punctures your family.

　　Guiyang at that time may not be too far away from Mr. Wang Yangming’s situation in Guiyang. If Mr. Wang Yangming crosses to today, it would be amazing to see Guiyang and the Dragon Field today. But at the same time, on the other hand, will he also have something that is not satisfied and not satisfied? I thought for a long time, and I said about three sentences:

　　The first sentence is that it should be an abundant but concise material life. In a place like Guizhou, if its products want to prosper endlessly, we may be sorry for nature and the surrounding provinces. If we want to develop the whole of China, maybe the earth can’t stand it, and maybe the resources of other countries can’t stand it. Therefore, I hope that we are "rich". This word is very important. It is very convenient for the elderly to see a doctor, and it is very convenient for children to study. I hope Guiyang is like this.

　　In the second sentence, I hope that the social life in Guiyang will be free and harmonious in the future, and the pluralistic existence of society can find its niche and form a common harmonious ecology. This is my dream for Guiyang’s future;

　　In the last sentence, I hope that my spiritual life is full and full. Enrichment means that every day the sun is a brand-new sun, and every day at sunset, we feel that this day has not been wasted. You are a person who creates beauty, you love nature and exercise, you like painting, you like music, and you can even play the piano.

　　Taken together, the above three sentences, I think it is actually the social ideal of China tradition from Confucius’ great harmony to Wang Yangming. If so, if Guiyang can go to the front, it can set an example for China. If China can do these things, the world will respect Chinese very much, and they will say that traditional culture has returned to China.

　　Open green wisdom

　　Wang Chun, Vice Mayor of Guiyang Municipal People’s Government:From the integration of city and nature, a model is the original old Guiyang; From the integration of cities and industries, we have a new Guiyang after the founding of the people’s Republic of China; Now we are all describing a big Guiyang, and its planning orientation and direction, I think there are three aspects: one is open Guiyang, the other is green Guiyang, and the third is smart Guiyang.

　　The first is openness. Historically, Guizhou has had two major opening-up processes. The first time was Zhu Yuanzhang’s transfer from the north to the south, and 300,000 troops went to Guizhou. This is a tunpu culture; The second big opening was the westward movement of the Anti-Japanese War before the founding of the People’s Republic of China, and many Guizhou people came there at that time after the founding of the People’s Republic of China. So now we are facing a new round of western development, a big opening. The state defines Guizhou as an inland open economic zone, and has issued a plan for land and sea passage, in which Guiyang has important opportunities. Because opening up has brought about entrepreneurship and suitable employment, I think Guiyang, which is open, is an entrepreneurial city.

　　The second aspect is green Guiyang. We all feel this deeply, especially from other places. When we arrive in Guiyang, it is really refreshing. Guiyang has a green environment, air and blue sky. Guiyang is an ecological city, a livable city and a healthy city. More and more people come to live in Guiyang, so living and working in Guiyang has good competitiveness.

　　The third aspect is wisdom Guiyang. If opening up may still lag behind other cities in the country, green may lead other cities in the country, and when it comes to big data, then we are on the same starting line as the whole country. Therefore, Guiyang in the future is also a digital city and a modern city.

　　Therefore, with the development goals, open Guiyang, green Guiyang and smart Guiyang also spur the municipal government to plan and build Guiyang better.

Guangzhou Automobile Chuanqi adds ＂new members＂, which is the first choice for urban white-collar commuters.

The appearance of the new car adopts Lingyun Wing 3.0 design language, its front grille is designed with multiple chrome-plated horizontal bars, which are connected with the headlight group as a whole, and its lower enclosure is designed through, and the C-shaped daytime running lights on both sides enhance the recognition of the front face. The side waistline extends from the front fender to the tail light group to create a dive visual effect, and the tail part adopts a through light group design, and the chrome-plated double exhaust enhances the sports atmosphere of the tail part.

In terms of interior, Chuanqi gm6 is mainly black, but it has been upgraded in details. The new car is equipped with 12.3-inch LCD central control panel, cool LCD instrument, panoramic image, front seat heating and other configurations. In addition, Chuanqi gm6 is also equipped with one-button start, electric seat adjustment and other configurations to provide drivers and passengers with a more comfortable travel environment.

The length of the car is 4793mm, the width of the car body reaches 1837mm, and the wheelbase is 2810mm, which is quite satisfactory. In the same class, the wheelbase of Chuanqi M6 ranks 15th. The design of skylight also increases the subjective space feeling of front and rear passengers. Among the models of the same price and class, the trunk volume of Chuanqi M6 ranks 6th. The shape is very regular, and the storage volume is absolutely no problem for daily use.

Chuanqi M6MAX 270T Premium Edition uses a 1.5 engine, with a maximum horsepower of 177 and a peak torque of 270, matching the wet dual clutch (DCT) gearbox. The whole power parameters are superior in power performance among engines of the same class, which can provide better power performance. Chuanqi M6′ s official measured zero acceleration score is 9.4S, ranking 21st among 120,000-180,000 MPV models.

Chuanqi M6 has complete active/passive safety configuration, includingAutomatic parking、Zero tire pressure endurance tire、Automatic parking、Steep slope descent、hill start assist control、knee airbag、HUD head-up display、Anti-lock braking (ABS)、Braking force distribution (EBD/CBC, etc.)、Brake assist (EBA/BAS, etc.)、Traction control (ASR/TCS, etc.)、Active noise reduction、Engine start and stop、Side safety air curtain、Wireless charging of mobile phone、night vision system、LED daytime running lights、Forward reversing radar、Tire pressure monitoring、Steering wheel heating、Body stability control (ESP/DSC, etc.)、Rear reversing radar、Fatigue reminder、Remote parking、Child seat interface、Lane keeping (LKAS)Equal configuration.

Among them,Automatic parkingYou can avoid stepping on the brakes for a long time or needing to pull frequently;Steep slope descentCan safely pass through steep slope road conditions at low speed;knee airbagReduce the injury of the car interior to the occupant’s knees in the secondary collision.

In addition to the above description, we can also go to the Easy Car Forum to browse more real car feedback from actual buyers, or use our experience.